Phenolphthalein
Based on 1 publication(s) in Google Scholar
Phenolphthalein is an acid-base indicator that is colorless in an acidic environment and pink in an alkaline environment. Phenolphthalein is genotoxic and potentially carcinogenic to mice. In addition, phenolphthalein is also a blood indicator.
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- Reinheit: 99.39%
- CAS. Nr.: 77-09-8
- Formel: C20H14O4
- Molecular Weight:318.33
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Phenolphthalein
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT4 | CC50 |
58 μM
Compound: 1a
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In vitro cytotoxicity against mock infected MT-4 cells.
In vitro cytotoxicity against mock infected MT-4 cells.
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[PMID: 10377217] |
Phenolphthalein (2.5-10 μg/ml, 24 h; 1.25-15 μg/ml, 8 d) induces an increase in transformed cells in the Syrian hamster embryo (SHE) cell transformation assay[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 77-09-8
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Appearance Solid
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Molecular Weight 318.33
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Formel C20H14O4
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Color White to off-white
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SMILES
O=C1OC(C2=CC=C(O)C=C2)(C3=CC=C(O)C=C3)C4=C1C=CC=C4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Phytomedicine
Xiaoer Qixing Cha alleviates functional constipation via regulating gut microbiota and short-chain fatty acids in mice. [Abstract]2025 Nov 25:148:157417. PMID: 41161186
Lösungsmittel & Löslichkeit
DMSO : ≥ 50 mg/mL (157.07 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (281 KB)
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SDS (604 KB)
- English - EN (604 KB)
- Français - FR (604 KB)
- Deutsch - DE (604 KB)
- Norwegian - NO (604 KB)
- Español - ES (604 KB)
- Swedish - SV (604 KB)
- Italian - IT (604 KB)
- Korean - KR (604 KB)
- Portuguese - PT (604 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Fleischmann C, et al. Color indicator for supramolecular polymer chemistry: phenolphthalein-containing thermo- and pH-sensitive N-(Isopropyl)acrylamide copolymers and β-cyclodextrin complexation. Macromol Rapid Commun. 2013 Jul 12;34(13):1085-9. [Content Brief]
[3]. Stoll R E, et al. Phenolphthalein and bisacodyl: assessment of genotoxic and carcinogenic responses in heterozygous p53 (+/−) mice and Syrian hamster embryo (SHE) assay[J]. Toxicological Sciences, 2006, 90(2): 440-450. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.1414 mL | 15.7071 mL | 31.4141 mL | 78.5353 mL |
| 5 mM | 0.6283 mL | 3.1414 mL | 6.2828 mL | 15.7071 mL | |
| 10 mM | 0.3141 mL | 1.5707 mL | 3.1414 mL | 7.8535 mL | |
| 15 mM | 0.2094 mL | 1.0471 mL | 2.0943 mL | 5.2357 mL | |
| 20 mM | 0.1571 mL | 0.7854 mL | 1.5707 mL | 3.9268 mL | |
| 25 mM | 0.1257 mL | 0.6283 mL | 1.2566 mL | 3.1414 mL | |
| 30 mM | 0.1047 mL | 0.5236 mL | 1.0471 mL | 2.6178 mL | |
| 40 mM | 0.0785 mL | 0.3927 mL | 0.7854 mL | 1.9634 mL | |
| 50 mM | 0.0628 mL | 0.3141 mL | 0.6283 mL | 1.5707 mL | |
| 60 mM | 0.0524 mL | 0.2618 mL | 0.5236 mL | 1.3089 mL | |
| 80 mM | 0.0393 mL | 0.1963 mL | 0.3927 mL | 0.9817 mL | |
| 100 mM | 0.0314 mL | 0.1571 mL | 0.3141 mL | 0.7854 mL |
Phenolphthalein Related Classifications
HY-D0211 Related Classifications
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