AQ-13
AQ-13 (Compound 7) is a Chloroquine (HY-17589A) analogue with anti-breast cancer property. AQ-13 shows antiproliferative activities against MDA-MB231 and MCF7 with GI50 of 27.81 and 17.85 μM. AQ-13 shows low cytotoxicity against non-cancerous breast epithelial cells MCF10A (GI50 = 65.26 μM). AQ-13 can be used for the research of breast cancer.
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- CAS. Nr.: 32571-49-6
- Formel: C16H22ClN3
- Molecular Weight:291.82
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF-10A | GI50 |
65.26 μM
Compound: 7
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Antiproliferative activity against human MCF10A cells after 48 hrs by SRB assay
Antiproliferative activity against human MCF10A cells after 48 hrs by SRB assay
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[PMID: 20561720] |
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 32571-49-6
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Molecular Weight 291.82
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Formel C16H22ClN3
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SMILES
ClC1=CC2=NC=CC(NCCCN(CC)CC)=C2C=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AQ-13 Related Classifications
HY-178822 Related Classifications
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