BQZ-485
BQZ-485 is a a potent GDI2 inhibitor through the interaction with Tyr245. BQZ-485 disrupts the intrinsic GDI2-Rab1A interaction, thereby abolishing vesicular transport from the endoplasmic reticulum (ER) to the Golgi apparatus and initiating subsequent paraptosis events.
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- CAS. Nr.: 1906915-49-8
- Formel: C32H39NO3
- Molecular Weight:485.66
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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GDI2 |
Chemical Information
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CAS. Nr. 1906915-49-8
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Molecular Weight 485.66
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Formel C32H39NO3
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SMILES
CC1=CC(C)=CC(COC2=CC3=C([C@](C[C@@H](O)C[C@@H]4C)([H])N4CC3)C=C2OCC5=CC(C)=CC(C)=C5)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)