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Art. -Nr.: HY-186298

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Brassicasteryl linoleate

Brassicasteryl linoleate is a cholinesterase inhibitor. Brassicasteryl linoleate inhibits acetylcholinesterase, butyrylcholinesterase and urease. Brassicasteryl linoleate inhibits lipid peroxidation. Brassicasteryl linoleate is applicable to research related to breast cancer, lung cancer and colon adenocarcinoma.

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CAS. Nr.: 73691-63-1
Formel: C₄₆H₇₆O₂
Molecular Weight:661.09

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Brassicasteryl linoleate Chemical Structure

CAS. Nr.: 73691-63-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]^[2]^[3]^[4]

AChE

BChE

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen :

AChE
BChE

Cellular Effect

Cell Line	Type	Value	Description	References
MCF7	IC50	67.20 μg/mL	Cytotoxic activity against human MCF-7 breast cancer cells assessed as reduction in cell viability by WST-1 assay. Cytotoxic activity against human MCF-7 breast cancer cells assessed as reduction in cell viability by WST-1 assay.	40513695
NCI-H1299	IC50	92.24 μg/mL	Cytotoxic activity against human H1299 lung cancer cells assessed as reduction in cell viability by WST-1 assay. Cytotoxic activity against human H1299 lung cancer cells assessed as reduction in cell viability by WST-1 assay.	40513695
L929	IC50	>200 μg/mL	Cytotoxic activity against murine L929 fibroblast cells assessed as reduction in cell viability by WST-1 assay, with no observed cytotoxic activity. Cytotoxic activity against murine L929 fibroblast cells assessed as reduction in cell viability by WST-1 assay, with no observed cytotoxic activity.	40513695
HeLa	IC50	>200 μg/mL	Cytotoxicity against human HeLa cervical cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay. Cytotoxicity against human HeLa cervical cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.	35218860
HT-29	IC50	73.2 μg/mL	Cytotoxicity against human HT29 colon adenocarcinoma cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay. Cytotoxicity against human HT29 colon adenocarcinoma cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.	35218860
MCF7	IC50	64.2 μg/mL	Cytotoxicity against human MCF7 breast cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay. Cytotoxicity against human MCF7 breast cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.	35218860

In Vitro

Brassicasteryl linoleate (compound 7) inhibits the viability of MCF-7 breast cancer cells with an IC₅₀ of 67.20 μg/mL and H1299 lung cancer cells with an IC₅₀ of 92.24 μg/mL, and is non-toxic to L929 murine fibroblast cells^[1].
Brassicasteryl linoleate (compound 3) (48 h) exhibits weak cytotoxicity against HT29 and MCF7 cancer cell lines, no cytotoxicity against HeLa cancer cells, and weak toxicity against PDF fibroblast cells, with IC₅₀ values of 73.2 µg/mL, 64.2 µg/mL, and 90.1 µg/mL, respectively^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 73691-63-1
Molecular Weight 661.09
Formel C₄₆H₇₆O₂
SMILES

C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)/C=C/[C@H](C)C(C)C)C
Structure Classification
- Steroids
Initial Source
- Microorganisms
from the mushroom Sarcosphaera crassa
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Kuş Ç, et al. Mycochemical investigation, antioxidant, cytotoxic and enzyme inhibition activities oftruffle Picoa lefebvrei. Steroids. 2025 Sep;221:109651.

[2]. Hammann S, et al. Gas chromatographic separation of fatty acid esters of cholesterol and phytosterols on an ionic liquid capillary column. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2015 Dec 15;1007:67-71.

[3]. Ullah Z, et al. Insight into isolation and elucidation of cytotoxic ergostanoids from the mushroom Sarcosphaera crassa (Santi) Pouzar: An edible mushroom. Steroids. 2022 May;181:108990.

[4]. Castellaneta A, et al. Exploration of the Lipid Profile of Edible Oleaginous Microgreens by Mass Spectrometry-Based Lipidomics. Journal of agricultural and food chemistry. 2024 May 22;72(20):11438-11451.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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Brassicasteryl linoleate

Alle Cholinesterase (ChE) Isoform-spezifische Produkte anzeigen