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Catumaxomab

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Based on 1 Customer Validation

Catumaxomab, a trifunctional IgG2 antibody, is composed of mouse and rat heavy and light chains and binds to human EpCAM and human CD 3 receptors. The Fc region of Catumaxomab region has binding affinity for FcγR1 (CD 64), FcγRIIA (CD 32a), and FcγRIII (CD 16). Catumaxomab can be used for anti-tumor research, especially epithelial cancers.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit : 99.82%
  • CAS. Nr.: 509077-98-9
  • Molecular Weight:146.73 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Catumaxomab
  • Experimental Validation Results for Catumaxomab
  • Experimental Validation Results for Catumaxomab
  • Catumaxomab Chemical Structure
    Catumaxomab Chemical Structure
CAS. Nr.: 509077-98-9
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Catumaxomab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    IgG2a-kappa/G2b-lambda

  • 1/16

    Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Catumaxomab at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG. Black - Unlabelled control, cells without incubation with primary antibody.

  • 1/16

    Immobilized EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P72367) can bind Catumaxomab. The EC50 for this effect is 579.8 ng/mL.

  • Catumaxomab Chemical Structure
    1/16
  • Catumaxomab
  • Flow Cytometry analysis of Jurkat cells labelling CD3 (red) with Catumaxomab at 1.0 μg/mL for 1 hour at 4°C. Goat Anti-Mouse IgG (PE) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG. Black - Unlabelled control, cells without incubation with primary antibody.
  • Immobilized EpCAM/TROP1 Protein, Human (Biotinylated, HEK293, His-Avi, HY-P72367) can bind Catumaxomab. The EC50 for this effect is 579.8 ng/mL.
  • IgG2a-kappa/G2b-lambda