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Art. -Nr.: HY-N8460

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Cortisol sulfate

(Synonyms: Cortisol 21-sulfate)

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin.

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CAS. Nr.: 1253-43-6
Formel: C₂₁H₃₀O₈S
Molecular Weight:442.52

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Cortisol sulfate Chemical Structure

CAS. Nr.: 1253-43-6

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Biologische Aktivität
- Beschreibung
- In Vivo
Chemical Information
Publications (1)
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Cortisol sulfate (Cortisol 21-sulfate) is a metabolite of Cortisol (HY-N0583). Cortisol sulfate is a specific ligand for intracellular transcortin^[1]^[2]^[3].

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen :

In Vivo

Cortisol sulfate (3 mg; i.m.; every other day; for 2-7 weeks) affects behavior through its direct action on the central nervous system^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Male Wistar-King rats^[4]
Dosage:

3 mg
Administration:

Intramuscular injection, every other day, for 2-7 weeks
Result:

Had significant stimulatory effects on the animal's exploratory behaviors (ambulation and rearing), when the treatments were started soon after weaning (postnatal day 21-24).

Chemical Information

CAS. Nr. 1253-43-6
Molecular Weight 442.52
Formel C₂₁H₃₀O₈S
SMILES

C[C@]([C@@]1(O)C(CO[S](=O)(O)=O)=O)(C2)[C@](CC1)([H])[C@@](CCC3=CC4=O)([H])[C@]([C@]3(CC4)C)([H])[C@H]2O
Synonyms

Cortisol 21-sulfate
Structure Classification
- Steroids
Initial Source
- Endogenous metabolite
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Proc Natl Acad Sci U S A

Progesterone activates GPR126 to promote breast cancer development via the Gi pathway. [Abstract]

2022 Apr 12;119(15):e2117004119. PMID: 35394864

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. C S Hall, et al. Simultaneous metabolism of cortisol sulfate and cortisol in normal human adults. J Clin Endocrinol Metab. 1970 Oct;31(4):439-44. [Content Brief]

[2]. S S Singer, et al. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology. 1976 Apr;98(4):963-74. [Content Brief]

[3]. T Hayashi, et al. Cortisol-21-sulfate (FS) is a specific ligand for intracellular transcortin: demonstration of three types of high affinity corticosteroid binders in bovine aortic cytosol by a combined use of FS and RU 28362. Endocrinology. 1990 Jan;126( [Content Brief]

[4]. S Miyabo, et al. Behavioral and other systemic effects of cortisol-21 sulfate. Horm Behav. 1972 Sep;3(3):227-36. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Cortisol sulfate

1 Cited Publications

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Cortisol sulfate

Publications Citing Use of MedChemExpress (MCE) Cortisol sulfate

Alle Endogenous Metabolite Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (1)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Cortisol sulfate Related Classifications

HY-N8460 Related Classifications