D-Ribose-5,5-C-d2
Based on 1 Customer Validation
D-Ribose-d2 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gl
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- Reinheit: 98.0%
- CAS. Nr.: 478506-32-0
- Formel: C5H8D2O5
- Molecular Weight:152.14
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 478506-32-0
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Unlabeled Cas 50-69-1
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Appearance Solid
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Molecular Weight 152.14
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Formel C5H8D2O5
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Color White to off-white
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SMILES
O=C[C@@H]([C@@H]([C@@H](C([2H])([2H])O)O)O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Lösungsmittel & Löslichkeit
H2O : 250 mg/mL (1643.22 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.5729 mL | 32.8645 mL | 65.7289 mL | 164.3223 mL |
| 5 mM | 1.3146 mL | 6.5729 mL | 13.1458 mL | 32.8645 mL | |
| 10 mM | 0.6573 mL | 3.2864 mL | 6.5729 mL | 16.4322 mL | |
| 15 mM | 0.4382 mL | 2.1910 mL | 4.3819 mL | 10.9548 mL | |
| 20 mM | 0.3286 mL | 1.6432 mL | 3.2864 mL | 8.2161 mL | |
| 25 mM | 0.2629 mL | 1.3146 mL | 2.6292 mL | 6.5729 mL | |
| 30 mM | 0.2191 mL | 1.0955 mL | 2.1910 mL | 5.4774 mL | |
| 40 mM | 0.1643 mL | 0.8216 mL | 1.6432 mL | 4.1081 mL | |
| 50 mM | 0.1315 mL | 0.6573 mL | 1.3146 mL | 3.2864 mL | |
| 60 mM | 0.1095 mL | 0.5477 mL | 1.0955 mL | 2.7387 mL | |
| 80 mM | 0.0822 mL | 0.4108 mL | 0.8216 mL | 2.0540 mL | |
| 100 mM | 0.0657 mL | 0.3286 mL | 0.6573 mL | 1.6432 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Ribose-5,5-C-d2 Related Classifications
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