ENT-C225
Based on 1 Customer Validation
ENT-C225 is an effective activator of TrkB neurotrophin receptor. ENT-C225 has high effect on activating TrkB receptor (TrkBR), and has good physicochemical properties and neuroprotective properties.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.16%
- CAS. Nr.: 2919962-53-9
- Formel: C26H40N4O5
- Molecular Weight:488.62
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
ENT-C225 (Compound 10) (1 µM; 24 h) significantly improves NIH-3T3 TrkB cytotoxicity and reduces cell mortality[1].
ENT-C225 (1 µM; 20 min) promotes TrkB receptor phosphorylation in NIH-3T3 TrkB cells and primary astrocytes[1].
ENT-C225 (500 pM-1 µM; 48 h) has significant neuroprotective effect and enhances in a dose-dependent manner. ENT-C225 promoting the accumulation of TAR DNA-binding protein 43 (TDP43) in the neural network and cytoplasm of spinal motor neurons[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2919962-53-9
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Appearance Solid
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Molecular Weight 488.62
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Formel C26H40N4O5
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Color White to off-white
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SMILES
O=C(C1=CC(C(NCCO)=O)=CC(C(NCC2CCN(CC2)CC3CCCCC3)=O)=C1)NCCO
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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