country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-183424

Copy Link Print Information

Hydrolapachol

Hydrolapachol is a mitochondrial respiratory chain inhibitor that targets the site between cytochrome b and c₁, and inhibits succinate oxidation in rat liver mitochondria. Hydrolapachol can be used in studies related to mitochondrial respiration.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3343-38-2
Formel: C₁₅H₁₆O₃
Molecular Weight:244.29

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Hydrolapachol Chemical Structure

CAS. Nr.: 3343-38-2

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

Hydrolapachol inhibits succinate oxidation in intact rat liver mitochondria with an IC₅₀ of 1.6 μg per mg protein^[1].
Hydrolapachol exerts a stronger inhibitory effect on succinate oxidation in intact rat liver mitochondria at lower pH, and this inhibition is completely reversed by bovine serum albumin, CCCP (HY-100941) and 2,4-dibromophenol, and partially reversed by 2,4-dinitrophenol; at low inhibitor concentrations, phosphate (or arsenate) is required to achieve maximal inhibition of succinate oxidation in intact rat liver mitochondria^[1].
Hydrolapachol can be prepared by platinum oxide-platinum black-catalyzed hydrogenation of Isolapachol, and can also be obtained by hydrogenation of lapachol^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3343-38-2
Molecular Weight 244.29
Formel C₁₅H₁₆O₃
SMILES

O=C1C(O)=C(CCC(C)C)C(C2=C1C=CC=C2)=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Howland JL. Inhibition of mitochondrial succinate oxidation by alkyl hydroxy naphthoquinones. Biochim Biophys Acta. 1965 Aug 24;105(2):205-13. [Content Brief]

[2]. Hooker SC. Condensation of Aldehydes with β-Hydroxy-α-naphthoquinone. Synthesis of Hydrolapachol. J Am Chem Soc. 1936;58(7):1163-1167.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen