Inophyllum B
Inophyllum B ((+)-Inophyllum B) is a potent HIV Reverse Transcriptase inhibitor with an IC50 value of 38 nM. Inophyllum B inhibits HIV-1 (IC50=1.4 μM) in vitro cell culture. Inophyllum B can be isolated from the acetone extract of the giant African snail, Achatina fulica.
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- CAS. Nr.: 41135-06-2
- Formel: C25H24O5
- Molecular Weight:404.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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HIV-1 1.4 μM (IC50) |
Reverse Transcriptase 38 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
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| MOLT-4 | IC50 |
1.4 μM
Compound: 2a (inophyllum B)
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Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay
Anti-HIV activity against HIV-1 in Molt-4 cells using 7-day infective assay
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[PMID: 7506311] |
| MOLT-4 | IC50 |
55 μM
Compound: 2a (inophyllum B)
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Tested for cytotoxicity in Molt-4 cells by XTT assay
Tested for cytotoxicity in Molt-4 cells by XTT assay
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[PMID: 7506311] |
Chemical Information
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CAS. Nr. 41135-06-2
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Molecular Weight 404.46
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Formel C25H24O5
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SMILES
O[C@@H]1C2=C(O[C@@H]([C@H]1C)C)C(C=CC(C)(O3)C)=C3C(C(C4=CC=CC=C4)=C5)=C2OC5=O
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Synonyms
(+)-Inophyllum B
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Inophyllum B Related Classifications
HY-142074 Related Classifications
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