KOSN 1724
KOSN 1724 is an anticancer agent. KOSN 1724 disrupts tubulin activity, stabilizes microtubules, and inhibits cancer cells proliferation. KOSN 1724 inhibits cytochrome P450 3A4, CYP2C9, and CYP2C19 activity. KOSN 1724 can be used for the research of cancer.
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- CAS. Nr.: 693272-98-9
- Formel: C27H39NO6
- Molecular Weight:473.60
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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CYP3A4 7.1 μM (IC50) |
CYP2C19 10.9 μM (IC50) |
CYP2C9 12.9 μM (IC50) |
KOSN 1724 potently inhibits the proliferation of MCF-7, NCI/ADR, A549, and Skov cancer cell lines with IC50 values of 2.5, 6.1, 5.3 and 5.3 nM[1].
KOSN 1724 inhibits CYP3A4, CYP2C9, and CYP2C19 enzyme activity with IC50 values of 7.1 μM, 12.9 μM, and 10.9 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 693272-98-9
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Molecular Weight 473.60
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Formel C27H39NO6
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SMILES
O=C(C[C@H](O)C1(C)C)O[C@H](/C(C)=C/C2=NOC(C)=C2)C/C=C(C)\C/C=C/[C@H](C)[C@H](O)[C@@H](C)C1=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
KOSN 1724 Related Classifications
HY-182602 Related Classifications
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