NA-17
NA-17 is a naphthalimide compound with anti-tumor activity and lower toxicity to normal cells like HL-7702 and WI-38. NA-17 exhibits a p53-dependent selective inhibition in various NSCLC cells, inducing the accumulation of active p53 in the mitochondria and nuclei of NSCLC cells. NA-17 can cause cell cycle arrest in the G1 phase, leading to apoptosis and cell death.
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- CAS. Nr.: 1708948-28-0
- Formel: C26H27N3O4
- Molecular Weight:445.51
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 1708948-28-0
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Molecular Weight 445.51
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Formel C26H27N3O4
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SMILES
O=C1C2=CC=CC3=C2C(C(N1CCC4=CC=C5OCOC5=C4)=O)=CC=C3NCCCN(C)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)