Petatewalide A
Petatewalide A is a bakkenolide-type sesquiterpene. Petatewalide A is isolated from Petasites tatewakianus. Petatewalide A inhibits NO production. Petatewalide A exhibits anticancer activity against cervical cancer, breast cancer, and Lewis lung cancer.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 1280717-80-7
- Formel: C22H30O6
- Molecular Weight:390.48
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Protokoll
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
93.3 μM
|
Cytotoxicity against human cervical carcinoma HeLa cells assessed by MTT assay, with cell viability measured after exposure to the compound.
Cytotoxicity against human cervical carcinoma HeLa cells assessed by MTT assay, with cell viability measured after exposure to the compound.
|
19686812 |
| MCF7 | IC50 |
114.3 μM
|
Cytotoxicity against human breast cancer MCF-7 cells assessed by MTT assay, with cell viability measured after exposure to the compound.
Cytotoxicity against human breast cancer MCF-7 cells assessed by MTT assay, with cell viability measured after exposure to the compound.
|
19686812 |
| BV-2 | IC50 |
84.1 μM
|
Inhibition of LPS-induced NO production in murine microglial BV-2 cells assessed by Griess reaction after incubation for 20 hrs.
Inhibition of LPS-induced NO production in murine microglial BV-2 cells assessed by Griess reaction after incubation for 20 hrs.
|
25188451 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 1280717-80-7
-
Molecular Weight 390.48
-
Formel C22H30O6
-
SMILES
O(C(C)=O)[C@H]1[C@@]2(C[C@@]3(C)[C@@]1([C@@H](OC(C=C(C)C)=O)CC[C@@H]3C)[H])C(=C)COC2=O
-
Structure Classification
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Dong XW, et al. Bakkenolides from Petasites tatewakianus. Fitoterapia. 2010 Apr;81(3):153-6. [Content Brief]
[2]. Wang M, et al. Characterization and NO inhibitory activities of chemical constituents from an edible plant Petasites tatewakianus. Journal of agricultural and food chemistry. 2014 Sep 24;62(38):9362-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Petatewalide A Related Classifications
HY-N21762 Related Classifications
Powered by Bioz