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Art. -Nr.: HY-P3386

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Selcopintide

Name: Selcopintide
Brand: MedChemExpress
SKU: HY-P3386
Availability: PreOrder

(Synonyms: Cpne7-DP)

Selcopintide (Cpne7-DP) consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin.

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CAS. Nr.: 2130912-34-2
Formel: C₆₂H₁₀₅N₂₁O₁₅
Molecular Weight:1384.63

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Selcopintide Chemical Structure

CAS. Nr.: 2130912-34-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Calcium Channel Isoform-spezifische Produkte anzeigen :

In Vitro

Selcopintide (Cpne7-DP) directly penetrates odontoblastic cell (MDPC-23 cells) ^[1].
Selcopintide (1, 10 μg) increases dspp promoter activity in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Selcopintide (Cpne7-DP; human DPCs with 10 µg subcutaneous transplantation in a 0.5% fibrin gel) promotes dentin-like tissue formation and the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Immunocompromised mice (NIH-bg-nu-xid)^[1]
Dosage:

10 µg
Administration:

Subcutaneous transplantation in a 0.5% fibrin gel
Result:

Promotes dentin-like tissue formation.
Promotes the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models.

Chemical Information

CAS. Nr. 2130912-34-2
Molecular Weight 1384.63
Formel C₆₂H₁₀₅N₂₁O₁₅
Synonyms

Cpne7-DP
Sequence

Lys-Tyr-Lys-Gln-Lys-Arg-Arg-Ser-Tyr-Lys
Sequence Shortening

KYKQKRRSYK
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (260 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Lee YS, et al. Tubular Dentin Regeneration Using a CPNE7-Derived Functional Peptide. Materials (Basel). 2020;13(20):4618. Published 2020 Oct 16. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise

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Selcopintide

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