TDPAM01
TDPAM01 is a positive allosteric modulator of AMPA receptor GluA2. TDPAM01 can specifically bind to the ligand-binding domain (LBD) of GluA2 and shows an IC50 of 13.4 nM for the GluA2 flop subtype. TDPAM01 can stabilize the activated conformation of GluA2 receptors, delay the receptor deactivation or desensitization process, maintaining the rapid excitatory synaptic transmission in the central nervous system.
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- CAS. Nr.: 2231103-08-3
- Formel: C18H22N4O4S2
- Molecular Weight:422.52
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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AMPA Receptor |
Chemical Information
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CAS. Nr. 2231103-08-3
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Molecular Weight 422.52
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Formel C18H22N4O4S2
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SMILES
O=S1(=O)NCN(C2=CC(=CC=C21)CCC3=CC=C4C(=C3)N(C)CNS4(=O)=O)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TDPAM01 Related Classifications
HY-165474 Related Classifications
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