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Art. -Nr.: HY-182756

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TREM2 modulator-1

TREM2 modulator-1 is a TREM2 modulator with an EC₅₀ categorized as A and Emax of ++, and can be found in relevant research contexts. TREM2 modulator-1 modulates Triggering Receptor Expressed on Myeloid Cells 2. TREM2 modulator-1 can be used for the research of neurodegenerative diseases.

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CAS. Nr.: 3070235-71-8
Formel: C₂₅H₂₂Cl₂FN₅O₂
Molecular Weight:514.38

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

TREM2 modulator-1 Chemical Structure

CAS. Nr.: 3070235-71-8

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target^[1]

TREM-2

Alle TREM receptor Isoform-spezifische Produkte anzeigen :

In Vitro

TREM2 modulator-1 (Example 18B) modulates TREM2 in HEK293/DAP12⁺TREM2 cells and activates phosphorylated Syk AlphaScreen signals, with an EC₅₀ of <10 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3070235-71-8
Molecular Weight 514.38
Formel C₂₅H₂₂Cl₂FN₅O₂
SMILES

FC1=C(C=CC(Cl)=C1)C2=NC([C@H]3C[C@@H](C4=CN(C5CC5)N=C4)OCC3)=CN6C2=NC(C)=C(Cl)C6=O
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Jakob Busch-Petersen, et al. Trem2 modulators. WO2025017059A1. WIPO (PCT). 2024-07-17.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biologische Aktivität
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- IC₅₀ & Target
- In Vitro
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TREM2 modulator-1

Alle TREM receptor Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

TREM2 modulator-1 Related Classifications

HY-182756 Related Classifications