UBP141
UBP141 is a GluN2C/2D (NR2C/2D)-preferring receptor antagonist, with Kds of 2.8, 4.2, 14.2, and 19.3 μM for NMDA receptor subtypes: GluN2C, 2D, 2A, and 2B, respectively. UBP141 can induce potent motor impairment in WT mice.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 344768-30-5
- Formel: C21H18N2O5
- Molecular Weight:378.38
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Biologische Aktivität
Chemical Information
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CAS. Nr. 344768-30-5
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Molecular Weight 378.38
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Formel C21H18N2O5
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SMILES
O=C(O)[C@@H]1N(CCN[C@@H]1C(O)=O)C(C2=CC=C3C=CC4=CC=CC=C4C3=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Morley RM, et, al. Synthesis and pharmacology of N1-substituted piperazine-2,3-dicarboxylic acid derivatives acting as NMDA receptor antagonists. J Med Chem. 2005 Apr 7;48(7):2627-37. [Content Brief]
[2]. Yamamoto H, et, al. Involvement of the N-methyl-D-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity. Mol Brain. 2013 Dec 16;6:56. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
UBP141 Related Classifications
HY-118574 Related Classifications
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