VGN50
VGN50 is a bioactive molecule that mimics the function of K-Rta and down-regulates MYC-mediated gene transcription. VGN50 has antitumor activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C121H218N46O32
- Molecular Weight:2829.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
VGN50 (24 μM, 24 h) Down-regulates the expression of MYC in BCBL-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:PEL xenograft mouse model[1]
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Dosage:10 mg/kg
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Administration:i.p., for 10 consecutive days
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Result:Ascites containing tumors accumulate without weight gain.
Chemical Information
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Molecular Weight 2829.31
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Formel C121H218N46O32
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Sequence
{d-Arg}-Lys-Lys-Arg-Arg-{Orn}-Arg-Arg-Arg-{βAla}-Leu-Ser-Ser-Ile-Leu-Gln-Gly-Leu-Tyr-Gln-Leu-Asp-Thr
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Sequence Shortening
{d-Arg}-KKRR-{Orn}-RRR-{βAla}-LSSILQGLYQLDT
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)