WJM-715
WJM-715 is an antimalarial agent with an EC50 of 0.015 μM by trageting STAR-related lipid transfer protein (PfSTART1) with a KD of 14 nM.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C19H22Cl2N4O4S
- Molecular Weight:473.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | EC50 |
>40 μM
Compound: 19b; WJM-715
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by Cell Titer-Glo assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 48 hrs by Cell Titer-Glo assay
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[PMID: 38554474] |
WJM-715 improves the aqueous solubility at pH 7.4 to 60 μM and the metabolic stability in rats hepatocytes to 68 μL/min/106cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 473.37
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Formel C19H22Cl2N4O4S
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SMILES
O=S(N1CCOCC1)(C2=C(Cl)C=CC(NC(C)(C)C(NC3=CN=CC(Cl)=C3)=O)=C2)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
WJM-715 Related Classifications
HY-161384 Related Classifications
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