ATN-161 (Standard)
ATN-161 (Standard) is the analytical standard of ATN-161 (HY-13535). This product is intended for research and analytical applications. ATN-161 is an antagonist of α5β1 integrin and αvβ3 integrin, as well as an inhibitor of fibrosis, an inhibitor of oxidative stress, a tight junction stabilizer, a mitochondrial integrity protector, an angiogenesis inhibitor and an antiviral agent. ATN-161 inhibits NLRP3, MAPK, and ROS. ATN-161 protects mice from SARS-CoV-2 infection. ATN-161 reduces infarct volume, alleviates edema, decreases immune cell infiltration, reduces the area of choroidal neovascularization lesions, lowers tumor microvessel density and viral load. ATN-161 can be used in research related to ischemic stroke, choroidal neovascularization, breast cancer, coronavirus disease 2019 (COVID-19), and liver metastasis of colorectal cancer.
For research use only. We do not sell to patients.
- CAS No.: 262438-43-7
- Formula: C23H35N9O8S
- Molecular Weight:597.64
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 262438-43-7
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Molecular Weight 597.64
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Formula C23H35N9O8S
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SMILES
O=C(N)C[C@@H](C(N)=O)NC([C@H](CS)NC([C@H](CO)NC([C@H](CC1=CNC=N1)NC([C@H]2N(C(C)=O)CCC2)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Keywords
- ATN-161 (Standard)
- 262438-43-7
- Reference Standards
- Integrin
- Apoptosis
- NOD-like Receptor (NLR)
- p38 MAPK
- Reactive Oxygen Species (ROS)
- SARS-CoV
- SARS coronavirus
- α5β1 integrin
- bEnd.3 cells
- ischemic stroke
- SARS-CoV-2
- colorectal liver metastases
- αvβ3 integrin
- choroidal neovascularization
- human choroidal endothelial cells
- VeroE6 cells
- MDA-MB-231 breast cancer cells
- Inhibitor
- inhibitor
- inhibit