ATX-IN-1
ATX-IN-1 (compound 35) is an inhibitor of ATX (IC50=0.7 nM) with anti-inflammatory activity. ATX-IN-1 can inhibit TGF-β/Smad pathway and reduce collagen deposition to alleviate Bleomycin (HY-108345)-induced fibrosis in mice. ATX-IN-1 has good oral bioavailability (F=69.5%) and particle stability.
For research use only. We do not sell to patients.
- Formula: C25H22N6O5
- Molecular Weight:486.48
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
IC50: 0.7 nM (ATX)[1]
Chemical Information
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Molecular Weight 486.48
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Formula C25H22N6O5
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SMILES
O=C1N(CCC2=C1N(C3=CN(COC)N=C3)N=C2C(NC4=CC=CC=C4C(O)=O)=O)C5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ATX-IN-1 Related Classifications
HY-170765 Related Classifications
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