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Cat. No.: HY-106799

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E-5110

E-5110 is an orally active non-steroidal antiflammatory agent. E-5110 increases contents of CYP2B and 3A.

For research use only. We do not sell to patients.

CAS No.: 107746-52-1
Formula: C₂₀H₂₉NO₃
Molecular Weight:331.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

E-5110 Chemical Structure

CAS No.: 107746-52-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

E-5110 is an orally active non-steroidal antiflammatory agent. E-5110 increases contents of CYP2B and 3A^[1].

IC₅₀ & Target^[1]

CYP3A

All Cytochrome P450 Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
RBL-1	IC₅₀	<1 μM Compound: E-5110	Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assay Inhibitory activity against cyclooxygenase in rat basophilic leukemia cells using prostaglandin G/H synthase assay	[PMID: 1847426]
RBL-1	IC₅₀	0.04 μM Compound: 1b	Inhibition of prostaglandin G/H synthase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187 Inhibition of prostaglandin G/H synthase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187	[PMID: 8295221]
RBL-1	IC₅₀	0.56 μM Compound: 1b	Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187 Inhibition of 5-lipoxygenase in intact rat basophilic leukemia cells stimulated with the calcium ionophore A-23187	[PMID: 8295221]
RBL-1	IC₅₀	8.1 μM Compound: E-5110	Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells Inhibitory activity against 5-lipoxygenase in rat basophilic leukemia cells	[PMID: 1847426]

Chemical Information

CAS No. 107746-52-1
Molecular Weight 331.45
Formula C₂₀H₂₉NO₃
SMILES

O=C1/C(CCN1OC)=C/C2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Daling Z, et al. Effect of E-5110, a novel non-steroidal anti-inflammatory drug, on trimethadione metabolism as an indicator of hepatic drug-oxidizing capacity in beagle dog. Xenobiotica. 1994 Mar;24(3):215-20. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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E-5110

All Cytochrome P450 Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

E-5110 Related Classifications

HY-106799 Related Classifications