AVID100 Antibody
AVID100 (MAB100) Antibody is a monoclonal antibody inhibitor targeting EGFR, which can be used to synthesize a novel antibody-drug conjugate (ADC) molecule AVID100. AVID100 Antibody is applicable to relevant research on breast cancer, head and neck cancer, and lung cancer.
For research use only. We do not sell to patients.
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All EGFR Isoforms
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Biological Activity
Human
AVID100 Antibody (MAB100) binds EGFR with an affinity of approximately 2 nM, acts as a full EGFR antagonist that blocks downstream signaling, and competes with EGF for EGFR binding[1].
AVID100 induces apoptosis and potent cytotoxicity (with IC50 values correlating with EGFR expression) in MDA-MB-468, H292, and FaDu cancer cells, but does not increase cytotoxicity or apoptosis in normal keratinocytes relative to unconjugated MAB100[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
ERBB1/EGFR/HER1
Unconjugated
The product can be reconstituted/diluted with sterile PBS or saline.
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Product Image
ELISA, FACS, Functional assay
Chemical Information
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SMILES
[AVID100 Antibody]
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Synonyms
MAB100 Antibody
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Formulation
Please refer to the lot-specific COA for specific buffer information.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AVID100 Antibody Related Classifications
HY-P991967 Related Classifications
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