Avosentan (Standard)
Avosentan (Standard) is the analytical standard of Avosentan (HY-15195). This product is intended for research and analytical applications. Avosentan is an orally active endothelin (ETA) receptor antagonist. Avosentan can block the ETA receptor, thereby reducing vascular contraction, and exerting a renal protective effect. Avosentan inhibits vascular contraction caused by ET-1 and alleviates the reduction in retinal and optic nerve head blood flow induced by it, lowering intraocular pressure in the glaucoma monkey model. Avosentan non-specifically blocks ETB receptors at high doses, inhibiting ETB-mediated diuresis and natriuresis, and may cause fluid retention. Avosentan can be used to reduce proteinuria with diabetic nephropathy, but induces significant fluid overload and congestive heart failure.
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- Pureté : 98%
- CAS No.: 290815-26-8
- Formule: C23H21N5O5S
- Masse moléculaire:479.51
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureté et documentation
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Help & FAQs
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HY-15403A
Atrasentan hydrochlorideETA Receptor Antagonist -
HY-A0013
BosentanET-1 Inhibtior -
HY-10088
ZibotentanETA Receptor Antagonist -
HY-15195
AvosentanETA Receptor Antagonist -
HY-15403
AtrasentanEndothelin Receptor Antagonist -
HY-14184
MacitentanETA/ETB Antagonist -
HY-A0013A
Bosentan hydrateET1 Receptor Antagonist -
HY-15894A
BQ-788ETB Receptor Antagonist -
HY-15895
AprocitentanEndothelin Receptor Antagonist -
HY-14184R
Macitentan (Standard)ETA/ETB Antagonist -
HY-13209
Ambrisentan -
HY-12378
BQ-123ETA Receptor Antagonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 290815-26-8
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Masse moléculaire 479.51
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Formule C23H21N5O5S
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SMILES
COC1=C(OC(C(NS(C2=NC=C(C=C2)C)(=O)=O)=NC(C3=CC=NC=C3)=N4)=C4OC)C=CC=C1
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Synonyms
Ro 67-0565 (Standard); SPP-301 (Standard)
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Avosentan (Standard) Related Classifications
HY-15195R Related Classifications
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