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Cat. No.: HY-120452

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AZD-8165

AZD-8165 is a highly selective neutral thrombin inhibitor. AZD-8165 is promising for research of cardiovascular diseases such as hypertension and heart failure.

For research use only. We do not sell to patients.

CAS No.: 1201686-72-7
Formula: C₂₃H₂₁ClFN₇O₄
Molecular Weight:513.91

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

AZD-8165 Chemical Structure

CAS No.: 1201686-72-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Clinical Trial
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

AZD-8165 is a highly selective neutral thrombin inhibitor. AZD-8165 is promising for research of cardiovascular diseases such as hypertension and heart failure^[1].

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 1201686-72-7
Molecular Weight 513.91
Formula C₂₃H₂₁ClFN₇O₄
SMILES

O=C([C@@H]1CC=NN1C([C@@H](C2=CC=C(F)C=C2)OC(CC)=O)=O)NCC3=CC(Cl)=CC=C3N4N=NN=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pokhodylo N, et al. The (1H-Tetrazol-1-yl) arenediazonium Salts as Convenient Reagents for Quinones Arylation: Synthesis of 1, 3-Benzoxathiol-2-ones and Naphtho [2, 1-d][1, 3] oxathiol-2-ones Bearing (1H-Tetrazol-1-yl) phenyl Motif[J]. Chemistry, 17(2): 304-314.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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