Copy Link Print Information

Barzolvolimab

(Synonyms: CDX-0159)
Customer Review

Based on 1 Customer Validation

Barzolvolimab is a humanized anti-KIT IgG1 monoclonal antibody. Barzolvolimab specificity and potently inhibits KIT activation by SCF. Barzolvolimab can reduce skin mast cells and disease activity in chronic inducible urticaria.

For research use only. We do not sell to patients.

  • Purity: 99.00%
  • CAS No.: 2438203-51-9
  • Molecular Weight:145.1 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Barzolvolimab
  • Experimental Validation Results for Barzolvolimab
  • Experimental Validation Results for Barzolvolimab
  • Experimental Validation Results for Barzolvolimab
  • Barzolvolimab Chemical Structure
    Barzolvolimab Chemical Structure
CAS No.: 2438203-51-9
Size
Price
Stock
Quantity
Amount: USD 0.00
Please select quantity
or
or

* Please select Quantity before adding items.

To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

Data Download
Barzolvolimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
  • Biological Activity
  • Chemical Information
  • Purity & Documentation
  • References
  • Help & FAQs
You May Still Need
Top Publications Citing

Use of MCE Products
Keywords
MOQ
Minimum order quantity
100 mg

Get Quote In-stock

Other size
Get Quote
Please select quantity
Amount: USD 0.00
Sign in to MedChemExpress Sign In
Register
Sign in to MedChemExpress
Register New Account

At least 6 characters

Personalize your experience, you are currently not signed in. For a better experience, please create an online profile, you can:

Obtain points redemption prizes
Check out faster
Add multiple shipping locations
View orders
Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD117/c-kit Protein, Human (HEK293, His, HY-P72752) can bind Barzolvolimab. The EC50 for this effect is 4.976 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5×106 THP-1 cells labeling Barzolvolimab (HY-P99462, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Barzolvolimab on ProA biosensor, can bind CD117/c-kit Protein, Human (HEK293, His, HY-P72752) with an affinity constant of 1.128E-09 M as determined in BLI assay.

  • Barzolvolimab Chemical Structure
    1/16
  • Barzolvolimab
  • Immobilized CD117/c-kit Protein, Human (HEK293, His, HY-P72752) can bind Barzolvolimab. The EC50 for this effect is 4.976 ng/mL.
  • Flow cytometric analysis of 1.5×106 THP-1 cells labeling Barzolvolimab (HY-P99462, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Barzolvolimab on ProA biosensor, can bind CD117/c-kit Protein, Human (HEK293, His, HY-P72752) with an affinity constant of 1.128E-09 M as determined in BLI assay.