BChE-IN-34
BChE-IN-34 is a potent and selective butyrylcholinesterase (BChE) inhibitor with an IIC50 of 25 nM. BChE-IN-34 shows excellent selectivity against BChE over acetylcholinesterase. BChE-IN-34 has neuroprotective and antioxidant effects.
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- CAS. Nr.: 2215768-12-8
- Formel: C21H19N5O2S2
- Molecular Weight:437.54
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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eqBCHE 25 nM (IC50) |
BChE-IN-34 (compound 35a) has moderate inhibition potency on β-Amyloid (1-42) (HY-P1363A) aggregation, and significant neuroprotective effect against SH-SY5Y cell injury induced by H2O2 and β-Amyloid (1-42)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2215768-12-8
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Molecular Weight 437.54
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Formel C21H19N5O2S2
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SMILES
O=C(CSC1=NN=C(COC2=CC=CC3=C2C=CC=C3)N1CC=C)NC4=NC=CS4
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)