BChE-IN-47
BChE-IN-47 (Compound 13) is a selective butyrylcholinesterase (BChE) inhibitor with an IC50 of 0.045 μM. BChE-IN-47 enhances the level of acetylcholine in the brain by selectively inhibiting BChE, thereby improving cognitive function. BChE-IN-47 can be used for the research of Alzheimer’s disease.
For research use only. We do not sell to patients.
- Formula: C17H17NO2S
- Molecular Weight:299.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BChE 0.045 μM (IC50) |
Chemical Information
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Molecular Weight 299.39
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Formula C17H17NO2S
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SMILES
O=C(N1CCCC1)OC2=CC=CC=C2/C=C/C3=CC=CS3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
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Protocol for Water Maze
The Morris Water Maze is a rodent spatial learning and memory assay in which a mouse or rat swims in opaque water to find an escape platform; in the hidden-platform version, the animal cannot see the platform and must use distal extra-maze cues to learn its fixed spatial location. The assay primarily measures hippocampus-dependent spatial learning during acquisition trials and spatial reference memory during probe trials after platform removal; readouts include escape latency, swim path length, swim speed, quadrant occupancy, platform-site crossings, and proximity to the former platform location.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BChE-IN-47 Related Classifications
HY-179726 Related Classifications
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