Beta-Asp-Arg
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Beta-Asp-Arg is a β-dipeptide and a product of cyanophycin degradation by cyanophycinase.
For research use only. We do not sell to patients.
- CAS No.: 2478-03-7
- Formula: C10H19N5O5
- Molecular Weight:289.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Beta-Asp-Arg serves as the substrate for Legionella longbeachae NSW150 dipeptidase Llo2535, whose hydrolysis of Beta-Asp-Arg supports the bacterium's nutrient utilization from cyanophycin[1].
Beta-Asp-Arg forms multiple hydrogen bond interactions with Synechocystis sp. PCC6803 cyanophycinase in a covalent co-complex structure[2].
Beta-Asp-Arg (200 μM) alone shows no measurable binding to inactive Synechocystis sp. PCC6803 cyanophycinase S132A, while the dimer (β-Asp-Arg)2 (300 μM) binds with high affinity (Kd = 9.3 μM) and the trimer (β-Asp-Arg)3 (200 μM) binds with lower affinity (Kd = 25.1 μM)[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2478-03-7
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Molecular Weight 289.29
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Formula C10H19N5O5
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Sequence
βAsp-Arg
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Sequence Shortening
βAsp-R
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (345.67 mM; Need ultrasonic)
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
[1]. Cazalet C, et al. Analysis of the Legionella longbeachae genome and transcriptome uncovers unique strategies to cause Legionnaires' disease. PLoS genetics. 2010 Feb 19;6(2):e1000851. [Content Brief]
[2]. Sharon I, et al. The structure of cyanophycinase in complex with a cyanophycin degradation intermediate. Biochimica et biophysica acta. General subjects. 2022 Nov;1866(11):130217. [Content Brief]
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.4567 mL | 17.2837 mL | 34.5674 mL | 86.4185 mL |
| 5 mM | 0.6913 mL | 3.4567 mL | 6.9135 mL | 17.2837 mL | |
| 10 mM | 0.3457 mL | 1.7284 mL | 3.4567 mL | 8.6418 mL | |
| 15 mM | 0.2304 mL | 1.1522 mL | 2.3045 mL | 5.7612 mL | |
| 20 mM | 0.1728 mL | 0.8642 mL | 1.7284 mL | 4.3209 mL | |
| 25 mM | 0.1383 mL | 0.6913 mL | 1.3827 mL | 3.4567 mL | |
| 30 mM | 0.1152 mL | 0.5761 mL | 1.1522 mL | 2.8806 mL | |
| 40 mM | 0.0864 mL | 0.4321 mL | 0.8642 mL | 2.1605 mL | |
| 50 mM | 0.0691 mL | 0.3457 mL | 0.6913 mL | 1.7284 mL | |
| 60 mM | 0.0576 mL | 0.2881 mL | 0.5761 mL | 1.4403 mL | |
| 80 mM | 0.0432 mL | 0.2160 mL | 0.4321 mL | 1.0802 mL | |
| 100 mM | 0.0346 mL | 0.1728 mL | 0.3457 mL | 0.8642 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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