1. Epigenetics
  2. Histone Demethylase
  3. Bizine

Bizine 

Cat. No.: HY-121095
Handling Instructions

Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects.

For research use only. We do not sell to patients.

Bizine Chemical Structure

Bizine Chemical Structure

CAS No. : 1591932-50-1

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Based on 1 publication(s) in Google Scholar

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Description

Bizine, a Phenelzine analogue, is a potent and selective LSD1 inhibitor, with a b>Ki of 59 nM. Bizine can modulate bulk histone methylation in cancer cells. Bizine shows neuroprotective effects[1].

IC50 & Target

Ki: 59 nM (LSD1)[1]

Molecular Weight

297.39

Formula

C18H23N3O

CAS No.
SMILES

NNCCC1=CC=C(NC(CCCC2=CC=CC=C2)=O)C=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Bizine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Bizine
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