BPR1J-340
BPR1J-340 is a potent FLT3 inhibitor with an IC50 of ~25 nM. BPR1J-340 inhibits the phosphorylation of FLT3 and STAT5 and triggered apoptosis in FLT3-ITD+ acute myeloid leukemia (AML) cells. BPR1J-340 exhibits significant anti-tumor activities.
For research use only. We do not sell to patients.
- CAS No.: 1395051-72-5
- Formula: C29H34N8O3
- Molecular Weight:542.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 1395051-72-5
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Molecular Weight 542.63
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Formula C29H34N8O3
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SMILES
O=C(NC1=NNC(C2=CC=C(CNC(NC3=NOC(CC)=C3)=O)C=C2)=C1)C4=CC=C(CN5CCN(C)CC5)C=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)