Bruceantarin
Bruceantarin is a potent antineoplastic agent. Bruceantarin can be used for leukemia and breast cancer research.
For research use only. We do not sell to patients.
- CAS No.: 41451-76-7
- Formula: C28H30O11
- Molecular Weight:542.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Bruceantarin exhibits potent antineoplastic activity in both MCF-7 and MDA-MB-231 cells, with IC50 values of 0.144 ± 0.039 μM and 0.238 ± 0.021, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 41451-76-7
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Molecular Weight 542.53
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Formula C28H30O11
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SMILES
COC([C@]12[C@@]3([H])[C@@]4(CO2)[C@@]([C@H]([C@@H]1O)O)([H])[C@@]5([C@@](C(C)=C(C(C5)=O)O)([H])C[C@@]4([H])OC([C@@H]3OC(C6=CC=CC=C6)=O)=O)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Ye QM, et al. Isolation, chemotaxonomic significance and cytotoxic effects of quassinoids from Brucea javanica. Fitoterapia. 2015 Sep;105:66-72. [Content Brief]
[2]. Kupchan SM, et al. Bruceantin, a new potent antileukemic simaroubolide from Brucea antidysenterica. J Org Chem. 1973 Jan 12;38(1):178-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bruceantarin Related Classifications
HY-N10591 Related Classifications
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