Fluciclovine
Fluciclovine is an amino acid analogue that can enter cells by targeting the amino acid transporters on the cell surface (mainly ASCT2 and LAT1). After being labeled with ¹⁸F, ¹⁸F-fluciclovine can be used as an imaging agent for positron emission tomography (PET) for prostate diagnosis imaging.
For research use only. We do not sell to patients.
- CAS No.: 222727-43-7
- Formula: C5H8FNO2
- Molecular Weight:133.12
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ASCT2 |
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 222727-43-7
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Molecular Weight 133.12
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Formula C5H8FNO2
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SMILES
OC([C@]1(C[C@H](C1)F)N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Laudicella R, et al. 18F-Facbc in Prostate Cancer: A Systematic Review and Meta-Analysis. Cancers (Basel). 2019 Sep 11;11(9):1348. [Content Brief]
[2]. Lowentritt BH, Kipper MS. Understanding and Improving 18F-Fluciclovine PET/CT Reports: A Guide for Physicians Treating Patients with Biochemical Recurrence of Prostate Cancer. Prostate Cancer. 2020 Apr 26;2020:1929565. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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