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Cat. No.: HY-111468

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Mcl1-IN-3

Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC₅₀ and K_i of 0.67 and 0.13 μM, respectively.

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CAS No.: 1814891-79-6
Formule: C₂₇H₂₂ClN₃O₄
Masse moléculaire:487.93

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Mcl1-IN-3 Chemical Structure

CAS No.: 1814891-79-6

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Mcl1-IN-3 is an inhibitor of Mcl1 extracted from patent WO2015153959A2, compound example 57; has an IC₅₀ and K_i of 0.67 and 0.13 μM, respectively.

IC₅₀ & Target

IC50: 0.67 μM (Mcl1)^[1]

Ki: 0.13 μM (Mcl1)

^[1]

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Chemical Information

CAS No. 1814891-79-6
Masse moléculaire 487.93
Formule C₂₇H₂₂ClN₃O₄
SMILES

CC1=NN(CC2=CC=C(OC3=CC(C)=C(Cl)C(C)=C3)C=C2)C4=C1C(C(O)=O)=CC(C5=CC=CO5)=N4
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Nikolovska-Coleska Z, et al. Pyrazolopyridines as inhibitors of Mcl-1 and and their preparation. WO2015153959A2

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Mcl1-IN-3

Voir tous les produits spécifiques à Isoform Bcl-2 Family

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Mcl1-IN-3 Related Classifications

HY-111468 Related Classifications