AChE-IN-101
AChE-IN-101 (Compound 7a) is an AChE inhibitor (IC50s = 0.21 μM (EeAChE); 13 nM (HsAChE)). AChE-IN-101 ameliorates Scopolamine (HY-N0296)-induced cognitive impairment. AChE-IN-101 can be used in the research of Alzheimer's disease.
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- Formule: C26H32N4O2
- Masse moléculaire:432.56
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
[1]|
EeAChE 0.21 μM (IC50) |
Chemical Information
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Masse moléculaire 432.56
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Formule C26H32N4O2
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SMILES
CN(C1=CC=C(C(C2=NN(C(C=C2)=O)CCC3CCN(CC3)CC4=CC=CC=C4)=C1)O)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)