Ale-a12K4
Ale-a12K4 is a peptide-derived ionizable lipid originating from a12K4. Ale-a12K4 mediates the targeted delivery of mRNA to bone tissues. Ale-a12K4 can be used for the preparation of lipid nanoparticles.
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- Formule: C68H138N6O11P2
- Masse moléculaire:1277.80
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Ale-a12K4 is conjugated with the bone-binding small molecule alendronic acid (HY-B0631) to serve as an inducer of bone-targeted mRNA expression; when formulated into lipid nanoparticles, it enhances mRNA expression in the femur and tibia and improves the specificity of mRNA expression within bone tissue[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 1277.80
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Formule C68H138N6O11P2
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SMILES
CCCCCCCCCCCCN(CCCC[C@H](NC(CCC(NCCCC(P(O)(O)=O)(O)P(O)(O)=O)=O)=O)C(N[C@H](C(N)=O)CCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)=O)CCCCCCCCCCCC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)