APL-1081
Based on 1 Customer Validation
APL-1081 (Mal-Exo-EVC-MMAE) is part of an antibody-conjugated active molecule (ADC). APL-1081 is conjugated with an ADC linker (peptide Mal-Exo-EEVC) and a potent tubulin polymerization inhibitor, MMAE (HY-15162).
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- Pureté: 99.79%
- CAS No.: 2921735-80-8
- Formule: C75H115N13O19
- Masse moléculaire:1502.79
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
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Activité biologique
Chemical Information
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CAS No. 2921735-80-8
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Appearance Solid
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Masse moléculaire 1502.79
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Formule C75H115N13O19
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Color White to off-white
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SMILES
O[C@@H](C1=CC=CC=C1)[C@@H](C)NC([C@H](C)[C@H]([C@@]2([H])N(CCC2)C(C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C([C@H](C(C)C)NC([C@H](C(C)C)N(C)C(OC(C3=CC=C(C=C3)NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC([C@@H](NC(C)=O)CCC(O)=O)=O)=O)=O)C(NCCCCCN4C(C=CC4=O)=O)=O)=O)=O)=O)=O)OC)=O
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Synonyms
Mal-Exo-EVC-MMAE
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
DMSO : 100 mg/mL (66.54 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.6654 mL | 3.3271 mL | 6.6543 mL | 16.6357 mL |
| 5 mM | 0.1331 mL | 0.6654 mL | 1.3309 mL | 3.3271 mL | |
| 10 mM | 0.0665 mL | 0.3327 mL | 0.6654 mL | 1.6636 mL | |
| 15 mM | 0.0444 mL | 0.2218 mL | 0.4436 mL | 1.1090 mL | |
| 20 mM | 0.0333 mL | 0.1664 mL | 0.3327 mL | 0.8318 mL | |
| 25 mM | 0.0266 mL | 0.1331 mL | 0.2662 mL | 0.6654 mL | |
| 30 mM | 0.0222 mL | 0.1109 mL | 0.2218 mL | 0.5545 mL | |
| 40 mM | 0.0166 mL | 0.0832 mL | 0.1664 mL | 0.4159 mL | |
| 50 mM | 0.0133 mL | 0.0665 mL | 0.1331 mL | 0.3327 mL | |
| 60 mM | 0.0111 mL | 0.0555 mL | 0.1109 mL | 0.2773 mL |