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ARS-1620 intermediate

ARS-1620 intermediate is an intermediate in the synthesis of a K-Ras^G12C inhibitor ARS1620 (HY-U00418).

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CAS No.: 1698027-20-1
Formule: C₁₇H₁₉BrClFN₄O₂
Masse moléculaire:445.71

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

ARS-1620 intermediate Chemical Structure

CAS No.: 1698027-20-1

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Activité biologique

Description

ARS-1620 intermediate is an intermediate in the synthesis of a K-Ras^G12C inhibitor ARS1620 (HY-U00418)^[1].

Chemical Information

CAS No. 1698027-20-1
Masse moléculaire 445.71
Formule C₁₇H₁₉BrClFN₄O₂
SMILES

ClC1=C(Br)C(F)=C(N=CN=C2N3CCN(C(OC(C)(C)C)=O)CC3)C2=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Janes, M. R., et al., (2018). Targeting KRAS Mutant Cancers with a Covalent G12C-Specific Inhibitor. Cell, 172(3), 578–589.e17. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Chemical Information
Pureté et documentation
Références

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