Atrazine
Based on 4 publication(s) in Google Scholar
Atrazine, a triazine herbicide, is principally used for control of certain annual broadleaf and grass weeds. Atrazine inhibits photophosphorylation but typically does not result in lethality or permanent cell damage in the short term.
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- Pureté: 99.32%
- CAS No.: 1912-24-9
- Formule: C8H14ClN5
- Masse moléculaire:215.68
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Stockage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Publications Citing Use of MedChemExpress (MCE) Atrazine
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Activité biologique
Atrazine (0-36.2 mg/kg, males, 0-45.3 mg/kg, females, mixed in the feed, daily for 24 months) suppresses the luteinizing hormone surge during the estrus cycle, leading to the maintenance of elevated blood levels of 17β-estradiol (E2) and prolactin in rats[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Beagle dogs[2]
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Dosage:0-33.73 mg/kg
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Administration:mixed in the feed, daily for 52 weeks
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Result:Induced cachexia, decreased food consumption and body weight gain, decreased erythroid parameters, total protein, albumin and calcium levels, and increased liver and ovary weights in dogs.
Chemical Information
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CAS No. 1912-24-9
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Appearance Solid
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Masse moléculaire 215.68
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Formule C8H14ClN5
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Color White to off-white
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SMILES
CC(NC1=NC(Cl)=NC(NCC)=N1)C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (4)
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Journal Impact Factor
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Most Recent
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J Hazard Mater
Atrazine exposure can dysregulate the immune system and increase the susceptibility against pathogens in honeybees in a dose-dependent manner. [Abstract]2023 Jun 15:452:131179. PMID: 36948121 -
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Insects
2025 May 3;16(5):491. PMID: 40429204 -
Solvant et solubilité
DMSO : 83.33 mg/mL (386.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureté et documentation
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Fiche technique (272 KB)
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SDS (622 KB)
- English - EN (622 KB)
- Français - FR (622 KB)
- Deutsch - DE (622 KB)
- Norwegian - NO (622 KB)
- Español - ES (622 KB)
- Swedish - SV (622 KB)
- Italian - IT (622 KB)
- Korean - KR (622 KB)
- Portuguese - PT (622 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Solomon KR , et al. Ecological risk assessment of atrazine in North American surface waters. Environ Toxicol Chem. 2013 Jan;32(1):10-1. [Content Brief]
[2]. Gammon DW, et al. A risk assessment of atrazine use in California: human health and ecological aspects. Pest Manag Sci. 2005 Apr;61(4):331-55. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.6365 mL | 23.1825 mL | 46.3650 mL | 115.9125 mL |
| 5 mM | 0.9273 mL | 4.6365 mL | 9.2730 mL | 23.1825 mL | |
| 10 mM | 0.4636 mL | 2.3182 mL | 4.6365 mL | 11.5912 mL | |
| 15 mM | 0.3091 mL | 1.5455 mL | 3.0910 mL | 7.7275 mL | |
| 20 mM | 0.2318 mL | 1.1591 mL | 2.3182 mL | 5.7956 mL | |
| 25 mM | 0.1855 mL | 0.9273 mL | 1.8546 mL | 4.6365 mL | |
| 30 mM | 0.1545 mL | 0.7727 mL | 1.5455 mL | 3.8637 mL | |
| 40 mM | 0.1159 mL | 0.5796 mL | 1.1591 mL | 2.8978 mL | |
| 50 mM | 0.0927 mL | 0.4636 mL | 0.9273 mL | 2.3182 mL | |
| 60 mM | 0.0773 mL | 0.3864 mL | 0.7727 mL | 1.9319 mL | |
| 80 mM | 0.0580 mL | 0.2898 mL | 0.5796 mL | 1.4489 mL | |
| 100 mM | 0.0464 mL | 0.2318 mL | 0.4636 mL | 1.1591 mL |
Atrazine Related Classifications
HY-N7091 Related Classifications
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