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Cat. No.: HY-182718

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AZD0011-PL

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 2374807-39-1
Formule: C₉H₁₉BN₂O₄
Masse moléculaire:230.07

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

AZD0011-PL Chemical Structure

CAS No.: 2374807-39-1

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

AZD0011-PL is a human arginase 1/ 2 inhibitor with IC₅₀ values of 0.01 μM and 0.02 μM. AZD0011-PL can be used for the researches of cancer, respiratory inflammatory disease^[1].

IC₅₀ & Target^[1]

hArginase 1

0.01 μM (IC₅₀)

hArginase 2

0.02 μM (IC₅₀)

In Vitro

AZD0011-PL (Compound 7) potently inhibits recombinant human Arginase 1 with an IC₅₀ of 0.01 μM and recombinant human Arginase 2 with an IC₅₀ of 0.02 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2374807-39-1
Masse moléculaire 230.07
Formule C₉H₁₉BN₂O₄
SMILES

OB(O)CCCC[C@]1(NC[C@@H](C1)N)C(O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Scott Nathan MLYNARSKI, et al. Arginase inhibitors and methods of use thereof. WO2019159120A1. 2020-08-17

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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