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Bavunalimab

(Synonyms: Anti-Human CTLA4xLAG3; XmAb-22841; Pavunalimab)
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Bavunalimab (Anti-Human CTLA4xLAG3) is a bispecific human anti-CTLA-4/LAG-3 monoclonal antibody. Bavunalimab activates T cells in NSG mice. Bavunalimab can be used for the research of cancer.

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  • Pureté: 99.408%
  • CAS No.: 2329669-78-3
  • Masse moléculaire:125.327 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Bavunalimab
  • Experimental Validation Results for Bavunalimab
  • Experimental Validation Results for Bavunalimab
  • Experimental Validation Results for Bavunalimab
  • Bavunalimab Chemical Structure
    Bavunalimab Chemical Structure
CAS No.: 2329669-78-3
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Bavunalimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    half-IGG1-kappa/(scFv-heavy-kappa)-h-CH2-CH3

  • 1/16

    Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Bavunalimab. The EC50 for this effect is 62.34 ng/mL.

  • 1/16

    Immobilized CTLA-4 Protein, Human (HEK293, HY-P72959) can bind Bavunalimab. The EC50 for this effect is 8.452 ng/mL.

  • 1/16

    Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Bavunalimab (HY-P99354). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Bavunalimab Chemical Structure
    1/16
  • Bavunalimab
  • Immobilized LAG-3 Protein, Human (HEK293, His, HY-P70722) can bind Bavunalimab. The EC50 for this effect is 62.34 ng/mL.
  • Immobilized CTLA-4 Protein, Human (HEK293, HY-P72959) can bind Bavunalimab. The EC50 for this effect is 8.452 ng/mL.
  • Flow Cytometry analysis of Raji cells labelling CTLA4 (red) with Bavunalimab (HY-P99354). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • half-IGG1-kappa/(scFv-heavy-kappa)-h-CH2-CH3