BAY-588
Based on 1 Customer Validation
BAY-588 is a selective inhibitor of GLUT1 with an IC50 value of 1.18μM.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98.99%
- CAS No.: 1799759-24-2
- Formule: C27H25F4N5O2
- Masse moléculaire:527.51
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
IC50=1.18μM（GLUT1)[1], IC50>10μM（GLUT2)[1], IC50=5.47μM（GLUT3)[1], IC50=0.5μM（GLUT4)[1]
Chemical Information
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CAS No. 1799759-24-2
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Appearance Solid
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Masse moléculaire 527.51
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Formule C27H25F4N5O2
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SMILES
O=C(N)C1=NC2=CC(F)=CC=C2C(C(NC3=C(N(N=C3C(F)(F)F)CC4=CC=C(C=C4)C(C)(C)C)C)=O)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (189.57 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8957 mL | 9.4785 mL | 18.9570 mL | 47.3925 mL |
| 5 mM | 0.3791 mL | 1.8957 mL | 3.7914 mL | 9.4785 mL | |
| 10 mM | 0.1896 mL | 0.9478 mL | 1.8957 mL | 4.7392 mL | |
| 15 mM | 0.1264 mL | 0.6319 mL | 1.2638 mL | 3.1595 mL | |
| 20 mM | 0.0948 mL | 0.4739 mL | 0.9478 mL | 2.3696 mL | |
| 25 mM | 0.0758 mL | 0.3791 mL | 0.7583 mL | 1.8957 mL | |
| 30 mM | 0.0632 mL | 0.3159 mL | 0.6319 mL | 1.5797 mL | |
| 40 mM | 0.0474 mL | 0.2370 mL | 0.4739 mL | 1.1848 mL | |
| 50 mM | 0.0379 mL | 0.1896 mL | 0.3791 mL | 0.9478 mL | |
| 60 mM | 0.0316 mL | 0.1580 mL | 0.3159 mL | 0.7899 mL | |
| 80 mM | 0.0237 mL | 0.1185 mL | 0.2370 mL | 0.5924 mL | |
| 100 mM | 0.0190 mL | 0.0948 mL | 0.1896 mL | 0.4739 mL |
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