BMY 42393
BMY 42393 is an orally active prostacyclin agonist which suppresses monocyte-macrophage atherogenic activity and cytokine production. BMY 42393 can be used for atherosclerosis research.
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- CAS No.: 136451-58-6
- Formule: C25H21NO4
- Masse moléculaire:399.44
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Platelet | EC50 |
1.2 μM
Compound: 47
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Antiaggregatory activity in platelet rich human plasma
Antiaggregatory activity in platelet rich human plasma
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[PMID: 21413808] |
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136451-58-6
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Masse moléculaire 399.44
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Formule C25H21NO4
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SMILES
O=C(O)COC1=CC=CC(CCC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)O2)=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kowala MC, et al. Prostacyclin agonists reduce early atherosclerosis in hyperlipidemic hamsters. Octimibate and BMY 42393 suppress monocyte chemotaxis, macrophage cholesteryl ester accumulation, scavenger receptor activity, and tumor necrosis factor production. Arterioscler Thromb. 1993 Mar;13(3):435-44. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BMY 42393 Related Classifications
HY-120309 Related Classifications
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