Brassicasteryl linoleate
Brassicasteryl linoleate is a cholinesterase inhibitor. Brassicasteryl linoleate inhibits acetylcholinesterase, butyrylcholinesterase and urease. Brassicasteryl linoleate inhibits lipid peroxidation. Brassicasteryl linoleate is applicable to research related to breast cancer, lung cancer and colon adenocarcinoma.
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- CAS No.: 73691-63-1
- Formule: C46H76O2
- Masse moléculaire:661.09
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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AChE |
BChE |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MCF7 | IC50 |
67.20 μg/mL
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Cytotoxic activity against human MCF-7 breast cancer cells assessed as reduction in cell viability by WST-1 assay.
Cytotoxic activity against human MCF-7 breast cancer cells assessed as reduction in cell viability by WST-1 assay.
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40513695 |
| NCI-H1299 | IC50 |
92.24 μg/mL
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Cytotoxic activity against human H1299 lung cancer cells assessed as reduction in cell viability by WST-1 assay.
Cytotoxic activity against human H1299 lung cancer cells assessed as reduction in cell viability by WST-1 assay.
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40513695 |
| L929 | IC50 |
>200 μg/mL
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Cytotoxic activity against murine L929 fibroblast cells assessed as reduction in cell viability by WST-1 assay, with no observed cytotoxic activity.
Cytotoxic activity against murine L929 fibroblast cells assessed as reduction in cell viability by WST-1 assay, with no observed cytotoxic activity.
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40513695 |
| HeLa | IC50 |
>200 μg/mL
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Cytotoxicity against human HeLa cervical cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
Cytotoxicity against human HeLa cervical cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
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35218860 |
| HT-29 | IC50 |
73.2 μg/mL
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Cytotoxicity against human HT29 colon adenocarcinoma cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
Cytotoxicity against human HT29 colon adenocarcinoma cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
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35218860 |
| MCF7 | IC50 |
64.2 μg/mL
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Cytotoxicity against human MCF7 breast cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
Cytotoxicity against human MCF7 breast cancer cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay.
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35218860 |
Brassicasteryl linoleate (compound 7) inhibits the viability of MCF-7 breast cancer cells with an IC50 of 67.20 μg/mL and H1299 lung cancer cells with an IC50 of 92.24 μg/mL, and is non-toxic to L929 murine fibroblast cells[1].
Brassicasteryl linoleate (compound 3) (48 h) exhibits weak cytotoxicity against HT29 and MCF7 cancer cell lines, no cytotoxicity against HeLa cancer cells, and weak toxicity against PDF fibroblast cells, with IC50 values of 73.2 µg/mL, 64.2 µg/mL, and 90.1 µg/mL, respectively[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 73691-63-1
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Masse moléculaire 661.09
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Formule C46H76O2
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SMILES
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)([H])[C@@]4([H])[C@](CC3)([C@@](CC4)([H])[C@H](C)/C=C/[C@H](C)C(C)C)C
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Structure Classification
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Initial Source
from the mushroom Sarcosphaera crassa
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Brassicasteryl linoleate Related Classifications
HY-186298 Related Classifications
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