Dehydrochenodeoxycholic acid
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Dehydrochenodeoxycholic acid is a ketone bile acid.
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- Pureté : 99.97%
- CAS No.: 859-97-2
- Formule: C24H36O4
- Masse moléculaire:388.54
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
10.93 μM
Compound: 29
|
Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assay
Agonist activity at human GPBAR1 expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by cAMP-Glo assay
|
[PMID: 25735208] |
Chemical Information
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CAS No. 859-97-2
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Appearance Solid
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Masse moléculaire 388.54
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Formule C24H36O4
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Color White to off-white
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SMILES
O=C1C[C@@]([H])(CC([C@@]2([C@@]3(CC[C@]4([C@]2(CC[C@@]4([C@@H](CCC(O)=O)C)[H])[H])C)[H])[H])=O)[C@]3(C)CC1
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Synonyms
5β-Cholanic acid-3,7-dione; 3,7-Dioxo-5β-cholanoic acid; 3,7-Diketochenodeoxycholic acid
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (257.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (269 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5737 mL | 12.8687 mL | 25.7374 mL | 64.3434 mL |
| 5 mM | 0.5147 mL | 2.5737 mL | 5.1475 mL | 12.8687 mL | |
| 10 mM | 0.2574 mL | 1.2869 mL | 2.5737 mL | 6.4343 mL | |
| 15 mM | 0.1716 mL | 0.8579 mL | 1.7158 mL | 4.2896 mL | |
| 20 mM | 0.1287 mL | 0.6434 mL | 1.2869 mL | 3.2172 mL | |
| 25 mM | 0.1029 mL | 0.5147 mL | 1.0295 mL | 2.5737 mL | |
| 30 mM | 0.0858 mL | 0.4290 mL | 0.8579 mL | 2.1448 mL | |
| 40 mM | 0.0643 mL | 0.3217 mL | 0.6434 mL | 1.6086 mL | |
| 50 mM | 0.0515 mL | 0.2574 mL | 0.5147 mL | 1.2869 mL | |
| 60 mM | 0.0429 mL | 0.2145 mL | 0.4290 mL | 1.0724 mL | |
| 80 mM | 0.0322 mL | 0.1609 mL | 0.3217 mL | 0.8043 mL | |
| 100 mM | 0.0257 mL | 0.1287 mL | 0.2574 mL | 0.6434 mL |