Deruxtecan-Eribulin
Based on 1 Customer Validation
Deruxtecan-Eribulin is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule Exatecan (HY-13631) (DNA topoisomerase I inhibitor) and Eribulin (HY-13442) (Microtubule inhibitor). Deruxtecan-Eribulin can be used for ADC synthesis.
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- Pureté : 95.83%
- Formule: C122H151FN16O32
- Masse moléculaire:2372.59
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Stockage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
Voir tous les produits spécifiques à Isoform Drug-Linker Conjugates for ADC
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Activité biologique
Description
IC50 & Target
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Topoisomerase I |
Dual payloads |
Chemical Information
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Appearance Solid
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Masse moléculaire 2372.59
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Formule C122H151FN16O32
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Color Off-white to light yellow
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SMILES
C=C1C[C@@]2([H])O[C@@]1([H])CC[C@]3([H])O[C@](C([C@H](C)C3)=C)([H])C[C@@]4([H])[C@]([C@@H](OC)[C@@H](C[C@H](O)CNC(OCC5=CC=C(NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NC(COC6=CC=C(CC(NC(CCCCCN7C(C=CC7=O)=O)=O)C(NCC(NCC(N[C@@H](CC8=CC=CC=C8)C(NCC(NCOCC(N[C@@H]9C%10=C%11C(C(N%12C%11)=CC([C@](O)(C(OC%13)=O)CC)=C%13C%12=O)=NC%14=CC(F)=C(C)C(CC9)=C%14%10)=O)=O)=O)=O)=O)=O)C=C6)=O)=O)=O)C=C5)=O)O4)([H])CC(C[C@]%15([H])O[C@]%16([H])[C@]%17([H])O[C@@]%18(O[C@@]%19([H])[C@@](O[C@]%17([H])[C@@]%19([H])O[C@@]%16([H])CC%15)([H])C%18)CC2)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvant et solubilité
In Vitro:
DMSO : 60 mg/mL (25.29 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (247 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.4215 mL | 2.1074 mL | 4.2148 mL | 10.5370 mL |
| 5 mM | 0.0843 mL | 0.4215 mL | 0.8430 mL | 2.1074 mL | |
| 10 mM | 0.0421 mL | 0.2107 mL | 0.4215 mL | 1.0537 mL | |
| 15 mM | 0.0281 mL | 0.1405 mL | 0.2810 mL | 0.7025 mL | |
| 20 mM | 0.0211 mL | 0.1054 mL | 0.2107 mL | 0.5269 mL | |
| 25 mM | 0.0169 mL | 0.0843 mL | 0.1686 mL | 0.4215 mL |
Deruxtecan-Eribulin Related Classifications
HY-164836 Related Classifications
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