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Cat. No.: HY-N21732

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Dihydrocucurbitacin E

Dihydrocucurbitacin E is a cucurbitacin anticancer agent found in the rhizomes of Begonia nantoensis. Dihydrocucurbitacin E exhibits cytotoxic effects on gastric cancer cells and nasopharyngeal carcinoma cells. Dihydrocucurbitacin E can be used in research on gastric cancer and nasopharyngeal carcinoma.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 28973-67-3
Formule: C₃₂H₄₆O₈
Masse moléculaire:558.71

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Dihydrocucurbitacin E Chemical Structure

CAS No.: 28973-67-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
NUGC-3	IC50	8.60 μg/mL	Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human NUGC-3 gastric carcinoma cells measured by cytotoxicity assay.	14993759
HONE1 cell line	IC50	2.68 μg/mL	Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay. Cytotoxic activity against human HONE-1 nasopharyngeal carcinoma cells measured by cytotoxicity assay.	14993759

In Vitro

Anti-cancer

Dihydrocucurbitacin E (up to 20 μg/mL) is cytotoxic to human NUGC-3 gastric carcinoma and HONE-1 nasopharyngeal carcinoma cells, with IC₅₀ values of 8.60 μg/mL and 2.68 μg/mL, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Cell Viability Determination by MTT Colorimetric Assay

Chemical Information

CAS No. 28973-67-3
Masse moléculaire 558.71
Formule C₃₂H₄₆O₈
SMILES

C[C@]12[C@@](C)([C@@]([C@@](C(CCC(OC(C)=O)(C)C)=O)(C)O)([C@H](O)C1)[H])CC(=O)[C@]3(C)[C@]2(CC=C4[C@]3(C=C(O)C(=O)C4(C)C)[H])[H]
Structure Classification
- Terpenoids
- Tetracyclic Triterpenoids
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wu PL, et al. Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis. Chemical & pharmaceutical bulletin. 2004 Mar;52(3):345-9.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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