Dioctyl phthalate-d4
Based on 1 Customer Validation
Dioctyl phthalate-d4 (DNOP-d4) is the d4-labeled Dioctyl phthalate (HY-W013755). Dioctyl phthalate (DNOP) is a plasticizer. Dioctyl phthalate increases the activities of alanine aminotransferase (ALT) and alkaline phosphatase (ALP) in the liver, as well as the levels of creatinine and urea in the kidney. Exposure to Dioctyl phthalate disrupts the homeostasis of the intestinal microbial community, increases the abundance of pathogenic bacteria, and reduces the abundance of beneficial bacteria such as Lactobacillus. Dioctyl phthalate induces significant and dose-dependent inflammatory responses in the liver, spleen and kidney of mice.
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- Pureté : 99.72%
- CAS No.: 93952-13-7
- Formule: C24H34D4O4
- Masse moléculaire:394.58
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Stockage:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 93952-13-7
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Unlabeled CAS 117-84-0
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Appearance Liquid (Density: 0.991 g/cm3)
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Masse moléculaire 394.58
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Formule C24H34D4O4
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Color Colorless to light yellow
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SMILES
O=C(C1=C([2H])C([2H])=C([2H])C([2H])=C1C(OCCCCCCCC)=O)OCCCCCCCC
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Synonyms
DNOP-d4; Di-n-octyl phthalate-d4; Phthalic acid dioctyl ester-d4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (253.43 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Pureté et documentation
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Fiche technique (270 KB)
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SDS (702 KB)
- English - EN (702 KB)
- Français - FR (702 KB)
- Deutsch - DE (702 KB)
- Norwegian - NO (702 KB)
- Español - ES (702 KB)
- Swedish - SV (702 KB)
- Italian - IT (702 KB)
- Korean - KR (702 KB)
- Portuguese - PT (702 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 2.5343 mL | 12.6717 mL | 25.3434 mL | 63.3585 mL |
| 5 mM | 0.5069 mL | 2.5343 mL | 5.0687 mL | 12.6717 mL | |
| 10 mM | 0.2534 mL | 1.2672 mL | 2.5343 mL | 6.3359 mL | |
| 15 mM | 0.1690 mL | 0.8448 mL | 1.6896 mL | 4.2239 mL | |
| 20 mM | 0.1267 mL | 0.6336 mL | 1.2672 mL | 3.1679 mL | |
| 25 mM | 0.1014 mL | 0.5069 mL | 1.0137 mL | 2.5343 mL | |
| 30 mM | 0.0845 mL | 0.4224 mL | 0.8448 mL | 2.1120 mL | |
| 40 mM | 0.0634 mL | 0.3168 mL | 0.6336 mL | 1.5840 mL | |
| 50 mM | 0.0507 mL | 0.2534 mL | 0.5069 mL | 1.2672 mL | |
| 60 mM | 0.0422 mL | 0.2112 mL | 0.4224 mL | 1.0560 mL | |
| 80 mM | 0.0317 mL | 0.1584 mL | 0.3168 mL | 0.7920 mL | |
| 100 mM | 0.0253 mL | 0.1267 mL | 0.2534 mL | 0.6336 mL |
Dioctyl phthalate-d4 Related Classifications
HY-W013755S Related Classifications
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Keywords
- Dioctyl phthalate-d4
- 93952-13-7
- DNOP-d4
- Di-n-octyl phthalate-d4
- Phthalic acid dioctyl ester-d4
- Isotope-Labeled Compounds
- Biochemical Assay Reagents
- Aminotransferases (Transaminases)
- Phosphatase
- Bacterial
- inflammation
- C57BL/6J male mice
- mouse liver
- mouse kidney
- mouse spleen
- alanine aminotransferase
- alkaline phosphatase
- Firmicutes/Bacteroidetes ratio
- gut microbiota
- ileum
- Inhibitor
- inhibitor
- inhibit