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Cat. No.: HY-W053641

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(E)-2-Nitrocinnamic acid

Name: (E)-2-Nitrocinnamic acid
Brand: MedChemExpress
SKU: HY-W053641
Price: 25.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1013-96-3
Formule: C₉H₇NO₄
Masse moléculaire:193.16

Stockage:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

(E)-2-Nitrocinnamic acid Chemical Structure

CAS No.: 1013-96-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Protocole (1)
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

(E)-2-Nitrocinnamic acid (Compound 1k) is an Acetylcholinesterase inhibitor. (E)-2-Nitrocinnamic acid is applicable to research related to Alzheimer's disease^[1].

IC₅₀ & Target

^[1]

AChE

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
BChE

In Vitro

(E)-2-Nitrocinnamic acid (10 μM) exhibits weak inhibition of AChE (8.52% inhibition at 10 μM) and negligible inhibition of BChE (2.11% inhibition at 10 μM), with a calculated AChE binding energy of -6.33 kcal/mol^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 1013-96-3
Appearance Solid
Masse moléculaire 193.16
Formule C₉H₇NO₄
SMILES

OC(/C=C/C1=C(C=CC=C1)[N+]([O-])=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.

Stockage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Protocole

All Animals and Diseases

Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Gießel JM, et al. Substituted cinnamic anhydrides act as selective inhibitors of acetylcholinesterase. Bioorg Chem. 2019;90:103058. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

Minimum order quantity

100 mg

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