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Cat. No.: HY-14889

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Fluciclovine

1 Cited Publications

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Fluciclovine is an amino acid analogue that can enter cells by targeting the amino acid transporters on the cell surface (mainly ASCT2 and LAT1). After being labeled with ¹⁸F, ¹⁸F-fluciclovine can be used as an imaging agent for positron emission tomography (PET) for prostate diagnosis imaging.

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CAS No.: 222727-43-7
Formule: C₅H₈FNO₂
Masse moléculaire:133.12

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Data Sheet (267 KB)

Fluciclovine Chemical Structure

CAS No.: 222727-43-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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- Essai clinique
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Description

IC₅₀ & Target^[2]

ASCT2

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ASCT2

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 222727-43-7
Masse moléculaire 133.12
Formule C₅H₈FNO₂
SMILES

OC([C@]1(C[C@H](C1)F)N)=O
Livraison

Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Life Metab

CLPTM1L modulates membrane lipid rafts to promote tumor EGFR signaling. [Abstract]

2026 May 20;5(4):loag012. PMID: 42325836

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Laudicella R, et al. 18F-Facbc in Prostate Cancer: A Systematic Review and Meta-Analysis. Cancers (Basel). 2019 Sep 11;11(9):1348. [Content Brief]

[2]. Lowentritt BH, Kipper MS. Understanding and Improving 18F-Fluciclovine PET/CT Reports: A Guide for Physicians Treating Patients with Biochemical Recurrence of Prostate Cancer. Prostate Cancer. 2020 Apr 26;2020:1929565. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Fluciclovine

1 Cited Publications

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Fluciclovine

Publications Citing Use of MedChemExpress (MCE) Fluciclovine

Voir tous les produits spécifiques à Isoform ASCT

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Fluciclovine Related Classifications

HY-14889 Related Classifications